| 张月震,柯磊,寇文冠,等.术前NLR联合PLR预测髋关节镜治疗股骨髋臼撞击综合征短期疗效的价值.骨科,2025,16(1): 27-31. |
| 术前NLR联合PLR预测髋关节镜治疗股骨髋臼撞击综合征短期疗效的价值 |
| The value of preoperative neutrophil to lymphocyte ratio, platelet to lymphocyte ratio in predicting the short-term outcomes of femoral acetabular impingment syndrome after hip arthroscopy |
| 投稿时间：2024-09-11 |
| DOI：10.3969/j.issn.1674-8573.2025.01.005 |
| 中文关键词: 中性粒细胞与淋巴细胞比值 血小板与淋巴细胞比值 股骨髋臼撞击综合征 髋关节镜 疗效 |
| 英文关键词: Neutrophil to lymphocyte ratio Platelet to lymphocyte ratio Femoral acetabular impingement syndrome Hip arthroscope Curative effect |
| 基金项目:河北省医学科学研究课题计划（20220320） |
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| 中文摘要: |
| 目的 探究术前中性粒细胞与淋巴细胞比值（neutrophil to lymphocyte ratio，NLR）、血小板与淋巴细胞比值（platelet to lymphocyte ratio，PLR）预测髋关节镜治疗股骨髋臼撞击综合征短期疗效的价值。方法 选择2022年1月至2024年1月于沧州市人民医院就诊并接受髋关节镜手术治疗的58例股骨髋臼撞击综合征病人作为研究对象。术前采用全自动血细胞分析仪检测所有病人的血常规，记录中性粒细胞、淋巴细胞和血小板绝对数，计算NLR和PLR。记录术前及术后6个月的改良Harris髋关节功能评分（modified Harris hip scores，mHHS），根据mHHS改善程度是否≥50%将病人分为疗效显著组和疗效不显著组。采用受试者特征（receiver operating characteristic，ROC）曲线评估术前NLR、PLR及两者联合对病人术后短期疗效的预测效能，采用Pearson相关性分析评估术前NLR、PLR与术后6个月mHHS评分的相关性。结果 术后6个月时58例病人的mHHS评分较术前显著升高，疗效显著者27例，疗效不显著者31例，疗效不显著组的术前NLR、PLR较疗效显著组显著增高，差异有统计学意义（P＜0.05）。术前NLR、PLR及两者联合预测病人术后疗效不显著的曲线下面积（area under curve，AUC）分别为0.735[95% CI（0.604，0.865）]、0.774[95% CI（0.654，0.894）]和0.876[95% CI（0.781，0.971）]。术前NLR、PLR均与术后mHHS评分呈显著负相关（r=-0.382，P=0.002；r=-0.488，P＜0.001）。结论 术前NLR、PLR与术后mHHS评分呈显著负相关，两者联合对股骨髋臼撞击综合征经髋关节镜治疗后的短期疗效具有一定预测价值。 |
| 英文摘要: |
| Objective To explore the value of preoperative neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in predicting the short-term efficacy of hip arthroscopy in the treatment of femoral acetabular impingment syndrome. Methods A total of 58 patients with femoral acetabular impingment syndrome who received hip arthroscopy in Cangzhou People's Hospital from January 2022 to January 2024 were selected as the study objects. The blood routine of all patients was detected by automatic blood cell analyzer before surgery. The absolute number of neutrophils, lymphocytes and platelets were recorded, and NLR and PLR were calculated. Modified Harris hip scores (mHHS) were recorded before and 6 months after surgery. Patients were divided into significant and insignificant effect groups according to whether the improvement of mHHS was ≥50%. The receiver operating characteristic (ROC) curve was used to evaluate the predictive efficacy of preoperative NLR, PLR and their combination on postoperative short outcome of patients. Pearson correlation analysis was used to evaluate the correlation between preoperative NLR, PLR and mHHS score 6 months after surgery. Results At 6th month after operation, mHHS score was significantly higher than that before operation, with 27 cases having demonstrated efficacy and 31 cases having no demonstrated efficacy. The preoperative NLR and PLR of the significant effect group were significantly higher than those of the insignificant effect group, with statistical significance (P＜0.05). The area under curve (AUC) of preoperative NLR, PLR and their combined prediction of postoperative efficacy was 0.735 [95% CI (0.604, 0.865)] and 0.774 [95% CI (0.654, 0.894)] and 0.876 [95% CI (0.781, 0.971)] respectively. Preoperative NLR and PLR were significantly negatively correlated with postoperative mHHS score (r=-0.382, P=0.002; r=-0.488, P＜0.001). Conclusion Preoperative NLR and PLR were significantly negatively correlated with postoperative mHHS scores, and the combination of the two had certain predictive value for the short-term efficacy of femoral acetabular impingement syndrome after hip arthroscopy. |
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