文章摘要
王斐,陶惠人.前路与后路融合治疗Lenke 1型青少年特发性脊柱侧凸效果的Meta分析.骨科,2023,14(2): 124-131.
前路与后路融合治疗Lenke 1型青少年特发性脊柱侧凸效果的Meta分析
Efficacy of Anterior or Posterior Fusion in Lenke 1 Adolescent Idiopathic Scoliosis: A Meta-Analysis
投稿时间:2023-02-21  
DOI:DOI:10.3969/j.issn.1674-8573.2023.02.007
中文关键词: 青少年特发性脊柱侧凸  前路  后路  胸腔镜  疗效  Meta分析
英文关键词: Adolescent idiopathic scoliosis  Anterior approach surgery  Posterior approach surgery  Thoracoscopy  Efficacy  Meta analysis
基金项目:深圳市科技计划项目基础研究重点项目(JCYJ20200109114233670)
作者单位E-mail
王斐 深圳大学总医院脊柱骨病科深圳 518071  
陶惠人 深圳大学总医院脊柱骨病科深圳 518071 huiren_tao@163.com 
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中文摘要:
      目的 比较前路与后路固定融合治疗Lenke 1型青少年特发性脊柱侧凸(AIS)的临床疗效。方法 在中国知网、万方数据库、PubMed、Web of Science、Cochrane library中检索有关前路与后路固定融合治疗Lenke 1型AIS的文献。从文献中提取主弯角度、手术时间、术中出血量、住院时间、融合节段以及术后并发症等数据,进行Meta分析。结果 共纳入文献7篇,共计388例,其中前路固定病人207例,后路固定病人181例。前路手术在改善胸椎后凸角[WMD=-6.81,95% CI(-10.33,-2.02),P<0.05]、减少融合节段[WMD=-2.98,95% CI(-4.29,-1.66),P<0.05]、减少手术出血[WMD=-616.04,95% CI(-1 082.93,-149.15),P<0.05]方面优于后路手术。后路手术在减少手术时间[WMD=96.75,95% CI(56.74,136.76),P<0.05]、减少并发症发生[RR=2.68,95% CI(1.67,4.31),P<0.0001]方面更具优势。结论 前路和后路手术均能满足冠状面矫形,前路手术可减少融合节段、减少出血量、维持更好的胸椎后凸,尤其前路胸腔镜辅助下可满足美容要求,具有独特优势。但后路手术耗时短、并发症少,仍是一种经典的治疗策略,需根据病情及病人诉求谨慎选择手术方案。
英文摘要:
      Objective To compare the clinical efficacy of anterior approach vs. posterior approach fixation fusion in the treatment of Lenke 1 type adolescent idiopathic scoliosis. Methods The literatures related to anterior and posterior internal fixation fusion therapy for Lenke 1 type adolescent idiopathic scoliosis from CNKI, Wanang Database, PubMed, Web of Science and Cochrane Library. Extraction from the literature included main curve degree, operation time, intraoperative blood loss, length of hospital stay, fusion segment, postoperative complications. The included studies were analyzed using RevMan 5.4 software. Results In the end, 7 references were included, all in English, with a total of 388 patients, including 207 patients with anterior approach and 181 patients with posterior approach. The anterior approach group was superior to the posterior approach group in terms of thoracic kyphosis [WMD=-6.81, 95% CI (-10.33, -2.02), P<0.05], fusion segment [WMD=-2.98, 95% CI (-4.29, -1.66), P<0.05], intraoperative blood loss [WMD=-616.04, 95% CI (-1 082.93, -149.15), P<0.05]. However, the posterior approach group had more advantages in operation time [WMD=96.75, 95% CI (56.74, 136.76), P<0.05], postoperative complications [RR=2.68, 95% CI (1.67, 4,31), P<0.0001]. Conclusion Both anterior and posterior surgery can achieve the correction of coronal deformities. Anterior approach can reduce fusion segments, reduce intraoperative blood loss, and maintain better thoracic kyphosis. Especially, it can meet the aesthetic requirements under the assistance of thoracoscopy. However, the posterior approach is still a classic treatment strategy with a shorter operation time and fewer complications, and the surgical plan should be carefully selected according to the condition and the patient's demands. Due to the limitation of quantity and quality of literature, the above conclusions need to be verified by more high-quality studies.
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