| 徐涛,王欢,方煌.以胸弯为主的青少年特发性脊柱侧凸对肺功能的影响研究.骨科,2021,12(2): 117-120. |
| 以胸弯为主的青少年特发性脊柱侧凸对肺功能的影响研究 |
| Influence of adolescent idiopathic scoliosis with thoracic curvature on pulmonary function |
| 投稿时间：2020-10-28 |
| DOI：10.3969/j.issn.1674-8573.2021.02.004 |
| 中文关键词: 青少年 脊柱侧凸 肺功能 Cobb角 |
| 英文关键词: Scoliosis Adolescent Pulmonary function Cobb angle |
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| 中文摘要: |
| 目的 分析以胸弯为主的青少年特发性脊柱侧凸（adolescent idiopathic scoliosis，AIS）对肺功能的影响。方法 回顾性分析2018年10月至2019年11月在我院确诊并接受治疗的31例AIS病人的临床资料，分析用力肺活量占预测值的百分比（FVC%pred）、第1秒用力呼气容积占预测值的百分比（FEV1%pred）等肺功能参数与年龄、身体质量指数（body mass index，BMI）、Cobb角、顶椎位置、椎体旋转程度、胸弯累及椎体数目的相关性，以及不同程度脊柱畸形对肺功能参数的影响。结果 31例病人的年龄为（15.81±4.51）岁（10~27岁）。FEV1%pred与Cobb角（r=-0.55，P=0.001）、Nash-Moe椎体旋转评级（r=-0.49，P=0.005）和胸弯累及椎体数目（r=-0.65，P=0.001）呈负相关。FVC%pred与Cobb角（r=-0.41，P=0.021）、Nash-Moe椎体旋转评级（r=-0.39，P=0.032）和胸弯累及椎体数目（r=-0.50，P=0.005）呈负相关；FVC%pred与BMI呈正相关（r=0.44，P=0.013）。年龄和顶椎位置与肺功能参数无相关性（P均＞0.05）。随着胸弯累及椎体数目自7个~9个增加，病人的FEV1%pred和FVC%pred均逐步下降，差异均有统计学意义（F=9.806，P=0.001；F=5.439，P=0.010）。随着Nash-Moe分级自0级~3级升高，FEV1%pred逐步下降，组间比较，差异有统计学意义（F=3.479，P=0.030）。结论 胸弯Cobb角大小、累及椎体数目与肺功能显著相关，可以作为肺功能障碍的预测因子。 |
| 英文摘要: |
| Objective To analyze the impact of adolescent idiopathic scoliosis (AIS) with thoracic curvature on pulmonary function, and to predict important factors that cause pulmonary dysfunction. Methods A retrospective study was conducted on 31 patients with AIS who underwent surgical treatment from October 2018 to November 2019. The correlation between the pulmonary function parameters such as FVC percent predicted (FVC%pred), the FEV1 percent predicted (FEV1%pred) and age, body mass index (BMI), Cobb angle, location of apical vertebrae, vertebral rotation degree, the number of involved vertebrae, and the influence of spinal deformity on pulmonary function parameters were analyzed. Results The age of 31 patients was (15.81±4.51) years (10-27 years). The Cobb angle (r=-0.55, P=0.001), vertebral rotation degree (r=-0.49, P=0.005) and the number of involved vertebrae (r=-0.65, P=0.001) were negatively correlated with FEV1%pred. The Cobb angle (r=-0.41, P=0.021), Nash-Moe vertebral rotation degree (r=-0.39, P=0.032) and the number of involved vertebrae (r=-0.50, P=0.005) were negatively correlated with FVC%pred. The BMI was positively correlated with FVC%pred (r=0.44, P=0.013). The location of apical vertebrae, and age were not correlated with pulmonary function (both P＞0.05). The FEV1%pred and FVC%pred decreased gradually as the number of vertebral bodies involved in thoracic curvature increased from 7 to 9 (F=9.806, P=0.001; F=5.439, P=0.010). With the Nash MOE grading increased from grade 0 to grade 3, FEV1%pred decreased gradually, and the difference was statistically significant (F=3.479, P=0.030). Conclusion The Cobb angle and the number of involved vertebrae are significantly correlated with pulmonary dysfunction, and can be used as predictors of pulmonary dysfunction. |
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