| 毕松超,陈涛,杨建东,等.骨质疏松椎体压缩性骨折行椎体成形术术后再骨折的危险因素分析.骨科,2017,8(6): 423-427. |
| 骨质疏松椎体压缩性骨折行椎体成形术术后再骨折的危险因素分析 |
| Risk factors of postoperative new vertebral compression re-fractures after percutaneous vertebroplasty |
| 投稿时间：2016-12-19 |
| DOI：10.3969/j.issn.1674-8573.2017.06.002 |
| 中文关键词: 椎体成形术 脊柱骨折 骨质疏松性骨折 再手术 危险因素 |
| 英文关键词: Vertebroplasty Spinal fractures Osteoporotic fractures Reoperation Risk factors |
| 基金项目:江苏省六大人才高峰资助项目（2014-WSN-076） |
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| 中文摘要: |
| 目的 探讨经皮椎体成形术（percutaneous vertebroplasty, PVP）和经皮椎体后凸成形术（percutaneous kyphoplasty, PKP）术后再骨折的相关危险因素。方法 回顾性分析2012年6月至2013年8月于苏北人民医院骨科行椎体成形术（PVP/PKP）治疗的骨质疏松性椎体压缩性骨折（osteoporosis vertebral compression fracture, OVCF）病人177例，男19例，女158例，年龄为52~91岁，伤椎总数为298个。所有病人患有骨质疏松症，均没有合并其他引起继发性骨质疏松或病理骨折的疾病，均顺利完成手术。根据术后是否发生再骨折将病人分为：再发骨折组（28例）和未再发骨折组（149例）。再发骨折组发生新发骨折，包括14例邻近椎体再骨折和14例跨跃式椎体再发骨折。对两组病人相关因素进行单因素和Logistic回归分析。结果 177例病人术后均获得随访，随访时间为6~24个月，平均（15.5±3.2）个月。单因素和Logistic回归分析显示：年龄、既往骨折病史、骨密度是病人出现再骨折的危险因素（均P＜0.05）。两组性别、基础椎体骨折数目、手术方式、骨水泥量比较，差异均无统计学意义（均P＞0.05）。进一步采用Logistic回归分析，发现年龄和骨密度为重要影响因素。结论 经皮椎体成形术后再发骨折的危险因素很多，高龄、低骨密度、既往存在骨折病史是PVP和PKP术后再发椎体骨折的独立危险因素。 |
| 英文摘要: |
| Objective To investigate the risk factors of postoperative new vertebral compression fractures after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP). Methods A total of 177 patients with vertebral compression fractures from June 2012 to August 2013 treated by PVP or PKP were retrospectively analyzed. Patients were divided into re-fracture group (28 cases) and control (no new fractures) group (149 cases). The related factors were analyzed by univariate analysis and logistic regression. Results All 177 cases were successfully operated. All patients were followed up for 6 to 24 months, average (15.5±3.2) months. Univariate and logistic regression analysis results showed that age, fractures history and BMD were the risk factors for new vertebral compression fractures after PVP or PKP. There were no statistically significant differences in sex, number of basic vertebral fractures, surgical procedures, and bone cement content between the two groups (P＞0.05 for all). Logistic regression showed that age and BMD were more important than others. Conclusion Older age, a history of fractures and low BMD are the risk factors for new vertebral compression fractures after PVP or PKP. |
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