| 张望,彭松林,镇万新,等.无体模法定量CT测量腰椎骨密度的可信度及可重复性研究.骨科,2016,7(6): 390-393. |
| 无体模法定量CT测量腰椎骨密度的可信度及可重复性研究 |
| Reproducibility of measurement of lumbar vertabal bone mineral density using quantitative CT without external reference phantom |
| 投稿时间：2016-04-11 |
| DOI：10.3969/j.issn.1674-8573.2016.06.002 |
| 中文关键词: 骨密度 定量CT 可信度 可重复性 |
| 英文关键词: Bone mineral density Quantitative CT Reliability Reproducibility |
| 基金项目:深圳市科技计划项目（GJHZ20140416123146582） |
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| 中文摘要: |
| 目的 评价无体模法定量CT（quantitative computed tomography, QCT）测量腰椎骨密度（bone mineral density, BMD; QCT-BMD）的同一位测量者内和3位测量者间BMD测量值的一致性和可重复性。方法 将31例患者的腰椎螺旋CT扫描数据传输至工作站进行BMD测量。由3位经过培训的脊柱外科医生（分别为测量者A、B、C）独立进行腰椎QCT-BMD测量，每位测量者对患者均测量2次。同一位测量者的2次测量和3位测量者间BMD测量值的差异用重复测量的方差分析比较，一致性分析用组内相关系数（intraclass correlation coefficient, ICC）描述。3位测量者间BMD测量值的可靠性分析用Cronbach’s α系数描述。结果 测量者A的2次腰椎BMD测量值分别为（67.14±26.71） mg/cc、（66.37±26.69） mg/cc，差值率为4.22%±2.55%（P=0.12, ICC=0.995）；测量者B的2次腰椎BMD测量值分别为（68.89±29.37） mg/cc、（68.54±28.98） mg/cc，差值率为5.08%±3.83%（P=0.56, ICC=0.994）；测量者C的2次腰椎BMD测量值分别为（69.31±26.72） mg/cc、（69.83±27.90） mg/cc，差值率为4.16%±3.03%（P=0.31, ICC=0.995）。3位测量者所测量的腰椎BMD平均值分别为（66.76±26.66） mg/cc、（68.71±29.13） mg/cc、（69.57±27.28） mg/cc（P=0.15, ICC=0.957, Cronbach’s α系数=0.985）。结论 无体模法QCT测量腰椎BMD具有较高的一致性和可重复性。 |
| 英文摘要: |
| Objective To evaluate the intra- and inter-observer consistency and reproducibility of bone mineral density (BMD) in lumbar vertebrae measured by quantitative CT without external reference phantom. Methods The CT data of 31 cases were transferred to a work station to measure lumbar BMDs. The BMDs were measured by three trained spine surgeons. Each observer performed the measurements of all subjects twice. Intra-observer and inter-observer variability was calculated using analysis of variance of the repeatedly measured results. The consistency was analyzed with the intra-class correlation coefficient (ICC). Reliability analysis in inter-observer was performed with Cronbach’s α coefficient. Results Data measured by Observer A were (67.14±26.71) mg/cc and (66.37±26.69) mg/cc ［difference: (4.22±2.55) %, P=0.12, ICC=0.995］, Observer B (68.89±29.37) mg/cc and (68.54±28.98) mg/cc ［difference: (5.08±3.83) %, P=0.56, ICC=0.994］, Observer C (69.31±26.72) mg/cc and (69.83±27.90) mg/cc ［difference: (4.16±3.03) %, P=0.31, ICC=0.995］, respectively. The mean lumbar BMDs by the three observers were (66.76±26.66), (68.71±29.13) and (69.57±27.28) mg/cc, respectively (P=0.15, ICC=0.957, Cronbach’s α coefficient=0.985). Conclusion High reproducibility and consistency in the measurement of lumbar BMD can be achieved with quantitative CT without external reference phantom. |
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